Specimen
A. Bone Marrow, Biopsy - 1 bone marrow biopsy left
B. Bone Marrow Aspirate Smear - 2 bone marrow aspirate smear - left
C. Blood, Peripheral - 3 Peripheral blood
Clinical Information
The patient is a 40 year old female who was diagnosed with metastatic breast carcinoma with bone and bone marrow metastasis in October 2009. At that time the tumor was estrogen and progesterone receptor positive and Her-2/neu negative by FISH. She was treated with radiation and chemotherapy. In November of 2009, the patient had 2 right breast biopsies which showed ductal carcinoma in one and invasive lobular carcinoma in the other. The patient has had a recent PET scan which by her report showed widely metastatic disease. The bone marrow is performed to assess metastatic disease and perform ER/PR and Her-2/neu on the tumor present.
Comment
This biopsy shows marked osteosclerosis and metastatic carcinoma consistent with breast carcinoma. Staining for estrogen weak positively in 2% of tumor cells. Progesterone staining was negative. Negative for Her-2/neu gene amplification, metastatic poorly differentiated carcinoma with breast primary.
1 comment:
Well this is not what you wanted for summer reading, is it? But there is one additional conclusion that the report seriously omitted: This proves that you are a miracle -- and that God has been traveling with you every step of the way. No doubt about it.
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