NO MUTATION DETECTED
Clinical Interpretation: This testing detects approximately 90% of individuals with inherited breast cancer. We are unable to estimate her remaining chance for carrying an undetectable mutation in a different gene due to her small paternal family structure..
It is highly unlikely that her sister or brother would have a detectable mutation
Application to Ms. Comeau-Nguyen: We still do not know the reason for her early onset breast cancer or the family history of breast cancer. At this time genetic testing has been unable to find an inherited cause of her breast cancer.
Application to her siblings: Her sisters and nieces would be considered to have an increased empirical risk for breast cancer based on this family history. They should meet with their care providers to discuss screening.
Should new genetic testing become available that would apply to her history, I will contact her as long as we have current contact information. Ms. Comeau-Nguyen should keep this report in a safe place and Penrose Hospital will keep a copy for a maximum of ten years. Should anyone else in the family develop cancer, she should contact me so we can determine if it would alter the family's risk analysis or indicate different genetic testing.
No comments:
Post a Comment